Osteoarthritis (allogeneic MSV)

IBGM Cell production room

Photo IBGM: Cell production room

The Instituto de Biología Genética Molecular de Valladolid (IBGM) [Valladolid Institute for Biology and Molecular Genetics] is sponsoring a clinical trial on the treatment of osteoarthritis of the knee through the injection into the joint of allogeneic stem cells, i.e. cells obtained from a donor.

The trial, in which Hospital Clínico Universitario de Valladolid and Centro Médico Teknon are participating, has been awarded funding by the Directorate-General for Pharmacy as part of its 2011 "Support for Independent Research" plan. Thirty patients have been included, fifteen of whom are in the control group being treated with hyaluronic acid.

The hypothesis is that allogeneic mesenchymal stem cells can be as effective as autologous cells and, because they do not cause  antigen reaction or rejection, may be useful for therapeutic application. The beneficiaries of this procedure could be viral load carriers in AIDS or hepatitis cases whose cells cannot be cultured in a cleanroom.

LINK to Registry ClinicalTrial.gov