Osteonecrosis Osteonecrosis from Femoral Head
Clinical trial on the application of cells for tissue repair (Tissue Repair Cell, TRC*) in osteonecrosis therapy of the femoral head Num Eudra CT: 2006-001286-42 Objectives Clinical trial with pilot characteristics to determine if an autologous TRC graft safely eliminates or delays the progression of osteonecrosis once the decompression surgery of the femoral head centre […]
Degenerative Disc Disease Chronic Low Back Pain with Cultured Mesenchymal Stem Cells
Efficacy of intra-discal injection of BM-MSC in subjects with chronic low back pain (LBP) due to degenerative disc disease (DDD) unresponsive (RESPINE) Clinical Trials. gov Identifier: NCT03737461 Num Eudra CT: 2017-002092-25 Objectives Clinical trial to evaluate the efficacy of the intra-discal injection of BM-MSC in subjects with chronic low back pain due to degenerative lumbar […]
Tendinopathy Patellar Tendon Regeneration
Treatment of refractory patellar tendinopathy with MSV*. Comparative study with LP-PRP (TENDO) Clinical Trials. gov Identifier: NCT03454737 Num Eudra CT: 2016-001262-28 Objectives Confirm the presence of patellar tendon GAP regeneration after the peritendinous infusion of MSV and compare it with the group of LP-PRP (Platelet-rich plasma and leukocyte-poor). The research has two objectives. First, to […]
Non-Union (Pseudarthrosis) Atrophic Pseudarthrosis
Phase II clinical trial to assess the effect of HC-SVT-1001 *(autologous adult trunk mesenchymal cells of adipose tissue expanded and included in βtricalcium-phosphate biomaterial) and HC-SVT-1002†(: allogenic adult trunk mesenchymal cells of adipose tissue expanded and included in βtricalcium-phosphate biomaterial.) in the surgical treatment of atrophic pseudarthrosis in long bones (Bonecure) Clinical Trials. gov Identifier: […]
Xerostomy Regenerating Glands with Cultured Mesenchymal Stem Cells
Phase II clinical trial to evaluate the effect and safety of MSV* in xerostomia ClinicalTrials.gov Identifier: NCT03743155 Nº EudraCT: 2018-001720-19 Objectives Clinical trial to evaluate the effect and safety of treatment with MSV in patients with radiation-induced xerostomia. Methodology Phase II, uncontrolled, open-label, prospective and unicentric clinical trial. 10 adult patients with xerostomy (grade 1-3) […]
Osteoarthritis Treatment with PRP
Clinical Trial to assess the effect of growth factors rich plasma in locomotor system pathology. Osteoarthritis Objectives Study to evaluate the potential anti-inflammatory effect, safety and efficacy of autologous Platelet-rich plasma and Leukocyte Poor (LP-PRP) treatment. In previous studies, LP-PRP has shown anti-inflammatory and pain relief effects, which are attributed to growth factors contained in […]
“Tennis leg” type muscle injuries Treatment with PRP
Randomized, multicentre, controlled, parallel, double-blind clinical trial with treatment masking to the evaluator, evaluating the efficacy of autologous Platelet-Rich Plasma (PRP) in the treatment of “tennis leg” type muscle tears Objectives The high vascularization of muscle leads to frequent hematomas when injured. This study is based on the hypothesis that when the muscle hematoma is […]
Tendinopathy Treatment with PRP
Clinical Trial to assess the effect of plasma rich in growth factors in locomotor system pathology. Tendinopathies Objectives Clinical Trial to evaluate the potential anti-inflammatory effect, safety and efficacy of autologous Platelet-rich plasma and Leukocyte Poor (LP-PRP) treatment. In previous studies, LP-PRP has shown anti-inflammatory and pain relief effects, which are attributed to growth factors […]